A sealable biohazard neutralizing bag formed of a flexible impermeable material capable of withstanding a neutralization process performed within the bag. The bag may include a vapor generator which, when activated, heats a fluid within the bag body to generate vapor to neutralize the contents of the bag. Alternatively a portable vapor generator may supply vaporized sterilant to the bag via a sealable port. Neutralization may be performed by: a. placing an item to be neutralized within the sealable bag； b. sealing a sealable opening of the bag； c. evacuating the bag via an outlet； and d. actuating the vapor generator to generate vapor such as to produce conditions sufficient to neutralize the item.
