Sandra Sofia Pereira Rodrigues;Lukas Adrian Kromer;Walter Anton Blättler;David John Gallo;Leo Edmond Otterbein;Carlos J. R. C. Romão
发明人:
Walter Anton Blättler,Carlos J. R. C. Romão,Sandra Sofia Pereira Rodrigues,Lukas Adrian Kromer,Leo Edmond Otterbein,David John Gallo
申请号:
US14112786
公开号:
US09163044B2
申请日:
2012.04.19
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided herein are novel carbon-monoxide releasing molecules (CO-RMs) of the Formula (I): and esters, amides, salts, solvates and hydrates thereof; wherein R1 and R2 are as described herein. Also provided are pharmaceutical compositions comprising these compounds, methods of their preparation, and their use in the treatment of liver disease and inflammation.