Cells coexpressing vitamin K reductase and vitamin K dependent protein and use thereof to improve the productivity of said vitamin K dependent protein

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专利权人:

UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

发明人:

STAFFORD, DARREL,LI, TAO

申请号：

PL07109353

公开号：

PL1842920T5

申请日:

2004.09.23

申请国别(地区):

PL

年份:

2018

代理人:

摘要：

The present invention provides a host cell comprising a heterologous nucleic acid encoding a vitamin K epoxide reductase (VKOR) and a nucleic acid encoding a vitamin K dependent protein, wherein the nucleic acids encoding both the VKOR and Vitamin K dependent protein are expressed in said host cell. The invention also provides methods for improving the productivity of vitamin K dependent protein expression in a host cell.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/