Peptides associated with HLA-DR MHC class II molecule and involved in rheumatoid arthritis

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专利权人:

Ewa Cairns;Jonathan Hill;David Bell

发明人:

Jonathan Hill,Ewa Cairns,David Bell

申请号：

US10794227

公开号：

US08198401B2

申请日:

2004.03.05

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Antigenic peptides that bind to MHC Class II molecules with the shared epitope referred to as HLA-DR molecules are disclosed. More specifically, are citrullinated antigenic peptides having an increased affinity for HLA-DR molecules and associated with Rheumatoid Arthritis. These novel peptides provide the basis for new methods of diagnosis and treatment of Rheumatoid Arthritis.

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