免疫調節劑化合物农业专利-农业专业知识服务系统

发明人:: LANGE, CHRISTOPHER,兰格　克里斯多夫,蘭格　克里斯多夫,MALATHONG, VIENGKHAM,马拉菘尔　维克汉姆,馬拉菘爾　維克漢姆,MCMURTRIE, DARREN J.,麦克默特里　达伦　J,麥克默特里　達倫　J,PUNNA, SREENIVAS,普纳　辛尼瓦斯,普納　辛尼瓦斯,SINGH, RAJINDER,斯颖　罗瑾德,斯穎　羅瑾德,YANG, JU,杨　菊,楊　菊,兰格克里斯多夫,蘭格克里斯多夫,马拉菘尔维克汉姆,馬拉菘爾維克漢姆,麦克默特里达伦 J,麥克默特里達倫 J,普纳辛尼瓦斯,普納辛尼瓦斯,斯颖罗瑾德,斯穎羅瑾德,杨菊,楊菊

摘要：: Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (II):(II) including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.本發明提供可用作免疫調節劑之化合物。該等化合物具有下式(II)：(II) 包含其立體異構體及醫藥上可接受之鹽，其中R1、R2a、R2b、R2c、R3、R4、R5、R6a、R6b、m及n係如本文所定義。亦揭示與該等化合物之製備及使用有關之方法，以及包括該等化合物之醫藥組合物。