Provided are a substance capable of binding to EGFR specifically with a high affinity and a pharmaceutical agent containing the substance. A peptide which contains at least an amino acid sequence is represented by the formula (1), (2) or (3), as described in the specification, and is composed of 12 to 50 amino acids:(SEQ ID NO: 55) X1-His-X2-X3-Asp-X4-X5-X6-X7-X8-Trp-His(1) (SEQ ID NO: 56) Phe-His-Asp-Trp-X11-Pro-X12-X13-X14-X15-X16-X17(2) (SEQ ID NO: 57) Leu-His-X21-Ser-X22-Trp-Met-X23-X24-X25-X26-X27(3).