DR GITANJALI S DEOKAR,DR PRAMOD GOVIND YEOLE,MR KIRAN BHAUSAHEB ERANDE
申请号：
IN3010/MUM/2011
公开号：
IN2011MU03010A
申请日:
2011.10.25
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
The present investigation is related to the fungal and yeast infections of the nails on the hands and the toes. The present formulations are in the paste as well as ready to mix powder form which is the combination of the three active ingredients Viz- Boerhaavia diffusa root extract, (Rakta punarnava/Ghetuli in marathi), Red lead/lead tetroxide powder (shendur in marathi), Calcium hydroxide powder (chuna in marathi). The paste form is preferred as the formulation can remain in contact of nail for longer period of time, and it will not be washed of easily. About 11 case studies were carried out taking the consent of the patients. It has been concluded by observing the patients that Red lead acts as wound healer which first helps in attachment of the detached nail plate from the nail bed. Boerhaavia difusa is antibacterial agent as well as antifungal agent playing major role if secondary bacterial infection persists with the onychomychosis, also it act as tissue rejuvenator. The rejuvenative action of punamava is via its opening and cleansing activity allowing effective nourishment and oxygen supply to the tissues. Where in fungi find difficult to survive in oxygen environment. Calcium hydroxide is found to have strong antifungal activity against the species Trichophyton rubrum, Candida albicans and Epidermohyton flocossum representive species most commonly found in the onychomychosis infected nail. It takes about a week or one month to get rid of the infection depending on the seriousness of the infection. The formulation is applied on infected nails and is kept covered overnight with cotton strip. Similarly apart from paste formulation ready to use powder mix of above mentioned ingredients, is also equally effective in treating the infection. Ready to use powder mix (sufficient quantity) is mixed with little amount of water ,mixture is applied on infected nail and tied up with the cotton strip and kept wet with water as possible. No side effects have been reported w
