vaccines comprising nonspecific nucleoside hydrolase polypeptides and sterol 24-c-methyl transferase (smt) for the treatment and diagnosis of leishmaniasis

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专利权人:

INFECTIOUS DISEASE RESEARCH INSTITUTE

发明人:

AJAY BHATIA,STEVEN G REED

申请号：

BR112013011420

公开号：

BR112013011420A2

申请日:

2011.11.07

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

Compositions and methods for preventing, treating and detecting leishmaniasis are disclosed. The compositions generally comprise fusion polypeptides comprising Leishmania antigens, in particular, SMT and NH antigens or immunogenic portions or variants thereof, as well as polynucleotides encoding such fusion polypeptides.

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