LEE, TAEKYU,BIAN, ZHIGUO,BELMAR, JOHANNES,CHRISTOV, PLAMEN P.,PELZ, NICHOLAS F.,SHAW, SUBRATA,KIM, KWANGHO,TARR, JAMES C.,OLEJNICZAK, EDWARD T.,ZHAO, BIN,FESIK, STEPHEN W.
申请号：
CA2943815
公开号：
CA2943815A1
申请日:
2015.03.26
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention provides for compounds that inhibit the activity of an anti-apoptotic Bcl-2 family member Myeloid cell leukemia-1 (Mcl-1) protein. The present invention also provides for pharmaceutical compositions as well as methods for using compounds for treatment of diseases and conditions (e.g., cancer) characterized by the over-expression or dysregulation of Mcl-1 protein.
