PURPOSE: A composition containing Perilla frutescens leaf extract is provided to ensure strong antioxidation effect and to prevent and treat liver diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating liver diseases contains Perilla frutescens leaf extract. The Perilla frutescens leaves are cultivated using sugar water. A functional food composition for protecting liver and improving liver function contains the Perilla frutescens extract. The pharmaceutical composition and food composition contain caffeic acid as an active ingredient.본 발명은 기능성 들깻잎 추출물을 함유하는 간 보호 및 간 질환 예방 또는 치료용 조성물에 관한 것이다.