Formulations à libération prolongée contenant des inhibiteurs de l'hormone de croissance analogues de la somatostatine

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专利权人:

CHEMI S.P.A.

发明人:

申请号：

EP05077559.2

公开号：

EP1787658B1

申请日:

2005.11.10

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Physically stable, transparent, biologically compatible, easy to prepare lipid solutions of somatostatin analogue inhibitors of growth hormone release are disclosed； they are suitable for subcutaneous or intramuscular administration and provide a sustained release of the active principle. The processes for the preparation of said formulations is also disclosed. These solutions contain one somatostatin analogue inhibitor of growth hormone release, preferably octreotide； a C 1 -C 8 alcohol, preferably ethanol； a phospholipid, preferably lecithin； and a C 1 -C 4 alkyl fatty acid ester, preferably isopropyl myristate.

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