CAR MACROPHAGE (MOTO-CAR) EN IMMUNOTHERAPIE

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专利权人:

BRIGHAM YOUNG UNIVERSITY

发明人:

O'NEILL, KIM,WEBER, SCOTT,ONEILL, KIM

申请号：

CA2998406

公开号：

CA2998406A1

申请日:

2016.10.13

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Modified macrophage immune cells are provided for treatment of cancer and other diseases. In particular said macrophages express chimeric antigen receptors (CAR). The single chain variable fragment (scFv) may be directed against thymidine kinase 1 (TK1)or hypoxanthine guanine phosphoribosyltransferase (HPRT). The signaling domain may be derived from a Toll-like receptor (TLR).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/