A system and method for motivating a particle, for example a drug molecule, to a predetermined location in three dimensional space by applying magnetic fields, which may be static or time-varying, to the particle. The magnetic fields may be applied by one or a plurality of magnets, and may be multipole of any order such as octopole or decapole. The electric current driving the magnet coils may be pulsed for inducing a voltage in the molecules to aid in motivation. In an exemplary embodiment of the invention in which the substance is a drug, for example a drug molecule or plurality of drug molecules, the magnets may be positioned outside the body of the person to be treated, and the magnetic field(s), which may be time-varying, are used to motivate the drug molecule(s) to a predetermined location in an animals body. The animal may be a human.