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Cytotoxic peptides and conjugates of these
专利权人:
Novartis AG
发明人:
GEIERSTANGER, Bernhard,GRUNEWALD, Jan,OU, Weijia,UNO, Tetsuo,WAN, Yongqin,WANG, Xing,JIN, Yunho
申请号:
ES14835606
公开号:
ES2758506T3
申请日:
2014.12.17
申请国别(地区):
ES
年份:
2020
代理人:
摘要:
and the use of such peptides in making immunoconjugates (i.e Antibody Drug Conjugates) Also described herein are immunoconjugates (i.e Antibody Drug Conjugates) comprising such novel cytotoxic peptide linked to an antigen binding moiety, such as an antibody; where such immunoconjugates are useful for treating cell proliferative disorders. The invention further provides pharmaceutical compositions comprising these immunoconjugates, compositions comprising the immunoconjugates with a therapeutic co-agent, and methods to use these immunoconjugates and compositions for treating cell proliferation disorders.
来源网站:
中国工程科技知识中心
来源网址:
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