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HIGH-THROUGHPUT MICROFLUIDIC-BASED METHODS FOR RECORDING DEFECATION MOTOR PROGRAM (DMP) EVENTS IN NEMATODES
专利权人:
NemaMetrix Inc.
发明人:
Kathryn McCormick,Trisha Brock
申请号:
US16452493
公开号:
US20200016592A1
申请日:
2019.06.25
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure provides methods and systems for performing, observing, and/or recording defecation motor program (DMP) events using microfluidic devices. The methods may be performed wherein the nematodes ingest fluorescent or color material and are then loaded in a microfluidic chip and stimulated to feed and defecate. DMP events are observed with use of a fluorescent microscope. In other methods, a microfluidic device with two or more electrodes is used to record electrical events of the DMP.
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