RÉDUCTION DES AGRÉGATS SOUS FORME DE PAILLETTES DANS DES COMPOSITIONS NANOPARTICULAIRES DE MÉLOXICAM

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专利权人:

ALKERMES PHARMA IRELAND LIMITED

发明人:

申请号：

EP10728470.5

公开号：

EP2435027B1

申请日:

2010.05.26

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising a nanoparticulate active agent, at least one surface stabilizer and a flake-like aggregation reducing agent, such as a buffer and a sugar. The nanoparticulate active agent compositions comprise particles of the active agent having an effective average particle size of less than about 2000nm.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/