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Fluorescent polybranched probes for detecting bacteria and/or fungi in vitro and in vivo
专利权人:
The University Court of the University of Edinburgh
发明人:
Mark Bradley,Annamaria Helena Lilienkampf,Nikolaos Avlonitis,Marc Vendrell Escobar,Neil Alexander McDonald,Christopher Haslett,Kanwaldeep Dhaliwal,Timothy Simon Walsh
申请号:
US15526117
公开号:
US10520504B2
申请日:
2015.11.13
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A probe for detecting bacteria and/or fungi in vitro and in vivo is provided, the probe having a core and a plurality of probe elements; each probe element within the plurality of probe elements extending from the core and having a fluorophore and a binding moiety, wherein the binding moiety is a bacteria binding moiety and selectively binds to bacteria and/or to fungi and not to animal cells. Methods of use of the probe and kits comprising the probe are also provided.
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