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Method to minimize chain scission and monomer generation in processing of poly(L-lactide) stent
专利权人:
Yunbing Wang
发明人:
Yunbing Wang,James Oberhauser
申请号:
US12905918
公开号:
US08496865B2
申请日:
2010.10.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Methods of fabricating an implantable medical devices such as stents made from biodegradable polymers are disclosed that reduce or minimize chain scission and monomer generation during processing steps. The method includes processing a poly(L-lactide) resin having an number average molecular weight between 150 to 200 kD in an extruder in a molten state. A poly(L-lactide) tube is formed from the processed resin and a stent is fabricated from the tube. The number average molecular weight of the poly(L-lactide) of the stent after sterilization is 70 to 100 kD.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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