A device and a method for detecting the presence of Cheyne-Stokes respiration from an oximetry signal and a ventilation flow signal are disclosed. The device identifies and removes artificial oximetry periods from the oximetry signal to produce an second signal and the device determines the mean length of contiguous periods of re-saturation in the second signal and returns a positive indication of Cheyne-Stokes respiration, if the mean length is greater than a predetermined threshold.