Cartilage oligomeric matrix protein (COMP)—growth factor complexes and uses thereof
- 专利权人:
- Dominik Haudenschild;Paul Di Cesare;Jasper Yik
- 发明人:
- Dominik Haudenschild,Paul Di Cesare,Jasper Yik
- 申请号：
- US13879399
- 公开号：
- US09133259B2
- 申请日:
- 2011.09.14
- 申请国别(地区):
- US
- 年份:
- 2015
- 代理人:
- 摘要：
- The present invention relates to protein complexes or scaffold comprising cartilage oligomeric matrix protein (COMP) polypeptides bound to one or more growth factors, and methods of their use in promoting chondrogenesis and/or osteogenesis, and repair of cartilage and bone lesions.
- 来源网站：
- 中国工程科技知识中心
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- METHOD FOR TREATMENT OF THE PROXIMAL FEMUR PATHOLOGICAL FRACTURE AFFECTED BY A METASTATIC LESION
- LESION POR ISQUEMIA/REPERFUSION.
- СПОСОБ ЛЕЧЕНИЯ ПАТОЛОГИЧЕСКОГО ПЕРЕЛОМА ПРОКСИМАЛЬНОГО ОТДЕЛА БЕДРЕННОЙ КОСТИ НА ФОНЕ МЕТАСТАТИЧЕСКОГО ПОРАЖЕНИЯ
- methods of identifying the ability of a stem cell to differentiate a cell into a chondrocyte, to differentiate ce = cell into a chondrocyte and to stem cell into a lesion tissue cell, to decrease chondrocyte death, to increase expression of at least a protein selected from the group consisting of tsp-2 and hb-egf from stem cell, sorting material that regulates stem cell activity and increasing expression of at least one selected from the group consisting of tsp -2 and hb-egf from stem cell and compositions for stimulating a cell to differentiate into a chondrocyte and to decrease chondrocyte d
- TREATMENT OF ENDOMETRIOSIS, ANGIOGENESIS AND/OR ENDOMETRIAL LESION GROWTH
