Metal Tricarbonyl Complexes Comprising Substituted Iminodiactic Acid Ligands and Uses as Radioisotope Tracers

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专利权人:

Emory University

发明人:

Jeffrey Klenc,Malgorzata Lipowska,Andrew Taylor

申请号：

US16822571

公开号：

US20200231615A1

申请日:

2020.03.18

申请国别(地区):

US

年份:

2020

代理人:

摘要：

This disclosure relates to compositions comprising substituted iminodiacetic acid ligands and metal tricarbonyl complexes containing the ligands and derivatives thereof. In certain embodiments, the metal tricarbonyl complexes are used as radioisotope tracers such as renal tracers. In certain embodiments, the metal complexes comprise 99mTc or Re. In certain embodiments, the ligands are substituted with a fluorine, a fluorine-18(F18) radioisotope, or other radionuclide.

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