Sung Wuk Kim,Seong Choon Choi,Ja Seong Koo,Sang Ouk Sun,Na Young Lee
申请号：
US14369406
公开号：
US20140377346A1
申请日:
2013.05.10
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Provided are an extended release preparation for oral administration of bosentan including bosentan, a pharmaceutically acceptable salt thereof or a solvate thereof as an active ingredient and a hydrophilic polymer as a sustained release excipient, and a method of manufacturing the same. Accordingly, the number of administrations of the bosentan, a pharmaceutically acceptable salt thereof or a solvate thereof may be reduced, thereby enhancing ease of administration and patient compliance. In addition, the extended release preparation for oral administration of bosentan may be effectively manufactured.
