ANTIBODY-CONJUGATED NANOPARTICLES AND MEDICAL USES THEREOF

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专利权人:

Trustees of Tufts College

发明人:

Sandra L. Ayres,Qiaobing Xu,Kristy L. Meadows

申请号：

US16320029

公开号：

US20190270822A1

申请日:

2017.07.11

申请国别(地区):

US

年份:

2019

代理人:

摘要：

An antibody-conjugated nanoparticle, 50 to 1000 nm in size, containing an anti-Mullerian hormone receptor II (AMHRII) antibody that is conjugated to a nanocomplex formed of a lipid-based delivery agent and a cytotoxin, the delivery agent and the cytotoxin being non-covalently bonded to each other. Also disclosed are a method of preparing such an antibody-conjugated nanoparticle and use thereof for inducing sterilization in a subject and for treating an AMHRII-associated condition.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/