作為ＰＩ３Ｋ抑制劑之雜環基胺农业专利-农业学术服务平台

发明人:: LI, YUN-LONG,李裕隆,YAO, WENQING,姚文清,COMBS, ANDREW P.,康堡　安德鲁Ｐ,康堡　安德魯Ｐ,YUE, EDDY W.,尤伊　艾迪Ｗ,ZHU, WENYU,朱文育,GLENN, JOSEPH,葛蓝　约瑟夫,葛藍　約瑟夫,MADUSKUIE, THOMAS P.,马德斯奎　汤玛士Ｐ,馬德斯奎　湯瑪士Ｐ,MEI, SONG,康堡安德鲁P,康堡安德魯P,尤伊艾迪W,葛蓝约瑟夫,葛藍約瑟夫,马德斯奎汤玛士P,馬德斯奎湯瑪士P

摘要：: The present invention provides heterocyclylamine derivatives of Formula I: wherein the variables are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.本發明提供式I之雜環基胺衍生物：其中變數係在本文中定義，該等衍生物調節磷酸肌醇3-激酶(PI3K)之活性且適用於治療與PI3K之活性相關之疾病，包括(例如)發炎性病症、免疫基病症、癌症及其他疾病。