NOUVEL ARNMI PRÉCURSEUR ET APPLICATION DE CE DERNIER DANS LE TRAITEMENT DE TUMEURS

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专利权人:

Ltd.;Jiangsu Micromedmark Biotech Co.

发明人:

ZHANG, Chenyu,ZENG, Ke,CHEN, Xi,ZHANG, Junfeng,LIANG, Hongwei

申请号：

EP15861258

公开号：

EP3222721A4

申请日:

2015.11.17

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Provided are a precursor miRNA and application thereof in a tumor treatment. The precursor miRNA from the 5' end to 3' end has a structure presented as formula I: B1 is anti-miRNA-214-5p； B2 is an essentially complementary sequence or a totally complementary sequence to B1, and B2 and C are not complementary； C is a sequence having a stem-loop structure； A1 and A2 are respectively RNA sequences having no or 4-5 bases freely selected bases respectively； the precursor miRNA shown can be processed to form anti-miRNA-214 in a host, and only anti-miRNA-214-5p but not anti-miRNA-214-3p is expressed in the anti-miRNA-214.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/