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HEMATOPOIETIC STEM AND PROGENITOR CELLS DERIVED FROM HEMOGENIC ENDOTHELIAL CELLS BY EPISOMAL PLASMID GENE TRANSFER
专利权人:
THE CHILDREN'S MEDICAL CENTER
发明人:
George Q. DALEY
申请号:
US16620938
公开号:
US20200199535A1
申请日:
2018.06.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Embodiments herein relate to in vitro production methods of hematopoietic stem cell (HSC) and hematopoietic stem and progenitor cell (HSPC) that have long-term multilineage hematopoiesis potentials upon in vivo engraftment. The HSC and HSPCs are derived from pluripotent stem cells-derived hemogenic endothelia cells (HE) by non-integrative episomal vectors-based gene transfer.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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