National Institute of Advanced Industrial Science and Technology
发明人:
申请号：
EP14791926.0
公开号：
EP2993182A1
申请日:
2014.05.02
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The present invention provides an immunity inducer and an immunity inducing method using same. The immunity inducer has an immunopotentiation effect on any target oligosaccharide antigen, in particular oligosaccharide antigens included in mammal-derived glycoprotein N-linked sugar chains； is capable of providing a monoclonal antibody having high specificity to and affinity with target oligosaccharide antigens； and has as an effective component thereof a glycolipid including a target oligosaccharide antigen (R) and indicated by general formula (2), or a salt thereof. General formula (2): R-Z-Y-CH(NH-CO-(CH2)n1-CH3-(CH2)n2-CH3 (in the formula, R indicates a straight-chain or branched oligosaccharide comprising 2-30 of at least one type of monosaccharide. Z indicates a single bond, O, S or NH, a linker bound to thiomethyl, amino methylated sugar alcohol. Y indicates -(CH2)m-. n1 indicates an integer of 2-40, n2 indicates an integer of 1-27, and m indicates an integer of 1-30).
