An interventional guidewire assembly with improved guidewire control includes a guidewire and a housing having a first opening that accommodates the guidewire and a second opening. The assembly further includes an actuator that passes through the second opening that is actuated by a finger in a direction substantially perpendicular to an axis of the guidewire. The assembly further includes a clamp operably coupled to the actuator that compresses the guidewire to couple the guidewire to the housing when pressure is applied to the actuator. The assembly further includes a return spring that supplies pressure to remove the clamp from the guidewire.
