The invention relates to a composition suitable for topical application comprising water, dimethyl isosorbide, a polyol and a phenolic or polyphenolic antioxidant. A method for producing a composition according to the invention is also part of the invention, as is a kit for making the composition. Optionally, the phenolic or polyphenolic antioxidant is provided in the form of a lyophilisate for the method and the kit. The use of the composition according to the invention for a treatment by topical application is also within the scope of the invention.本發明揭露包含水、二甲基異山梨醇、多元醇、及酚類抗氧化劑或多酚類抗氧化劑的局部施用組成物。本發明的一部分也包含製造根據本發明之組成物之方法,像是用於製造所述組成物之套組。選擇性地,酚類抗氧化劑或多酚類抗氧化劑係以凍乾物的形式提供於所述方法及所述套組中。本發明的範疇亦包含根據本發明之組成物透過局部施用而用於治療的用途。