Edward R Flynn,Victor Gerald Grafe,Steven C. Miller
申请号:
US14058050
公开号:
US20140112872A1
申请日:
2013.10.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides methods and apparatuses for detecting, measuring, or locating cells or substances present in even very low concentrations in vivo in subjects, using targeted magnetic nanoparticles and special magnetic systems. The magnetic systems can comprise magnetizing subsystems and sensors subsystems, including as examples SQUID sensors and atomic magnetometers. The magnetic systems can detect, measure, or location particles bound by antibodies to cells or substances of predetermined types. Example magnetic systems are capable of detecting sub-nanogram amounts of these nanoparticles.