An arrangement for the sterile handling of a non-sterile endoscope in a sterile environment comprises a sterile endoscope sheath for accommodating the endoscope and a cable via which the endoscope is connectable to a control unit, the arrangement further comprising a sterile cable sheath for accommodating at least a portion of the cable, wherein the endoscope sheath comprises a first sterile lock comprising at least one first sterile flap which in the closed state shields the endoscope arranged in the endoscope sheath in a sterile manner. The cable sheath comprises a second sterile lock having a second sterile flap which in a closed state shields the cable arranged in the cable sheath and/or a plug connector present on the arranged cable in a sterile manner. When connecting the cable or the plug connector to the endoscope, a movement of the first sterile flap from the closed state into an open state takes place and a movement of the second sterile flap from the closed state into an open state takes place so that a direct coupling of the cable to the endoscope or of the plug connector connected to the cable to a complementary plug connector of the endoscope is possible.
