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HUMANIZED C-KIT ANTIBODY
专利权人:
AMGEN INC.
发明人:
NG, GORDON,SHEN, WENYAN
申请号:
NZ59496807
公开号:
NZ594968A
申请日:
2007.04.24
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
594968 Disclosed is a nucleic acid encoding an antibody heavy chain that binds c-Kit comprising an amino acid sequence at least 95% identical to the amino acid sequence set forth in SEQ ID NO: 4 (MDWTWRVFCLLAVAPGAHSQVQLVQSGAEVKKPGASVKVSCKASGYTFTSYNMHWVRQAPGQGLEWMGVIYSGNGDTSYNQKFKGRVTITADKSTSTAYMELSSLRSEDTAVYYCARERDTRFGNWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYQSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK). Further disclosed is a nucleic acid comprising a nucleic acid sequence at least 95% identical to the nucleic acid set forth in SEQ ID NO: 3, wherein said nucleic acid encodes an antibody heavy chain that binds c-Kit.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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