CHROMENONE DERIVATIVES AS TRPV3 ANTAGONISTS农业专利-农业学术服务平台

发明人:: CHAUDHARI, SACHIN SUNDARLAL,乔德阿里萨钦孙达尔拉,喬德阿裏薩欽孫達爾拉,THOMAS, ABRAHAM,托马斯亚伯拉罕,托馬斯亞伯拉罕,KADAM, ASHOK BHAUSAHEB,卡达姆阿肖克巴萨赫伯,卡達姆阿肖克巴薩赫伯,DHONE, SACHIN VASANTRAO,德霍恩萨钦瓦萨特洛,德霍恩薩欽瓦薩特洛,ADIK, BHARAT GA

摘要：: The present invention provides a transient receptor potential vanilloid (TRPV) modulator of formula (I). In particular, the compound described herein is useful for treating or preventing diseases, conditions and/or disorders modulated by the TRPV3. Also provided herein are processes for preparing the compound described herein, an intermediate used in its synthesis, a pharmaceutical composition thereof, and a method for treating or preventing diseases, conditions and/or disorders modulated by the TRP V3.本發明提供了式(I)的瞬時受體電位香草素(TRPV)調節劑。特別地,本文所述的化合物可用於治療或預防由TRPV3調節的疾病、病症和/或障礙。同時,本文也提供了製備本文所述的化合物的方法、在其合成中所用的中間體、其藥物組合物以及治療或預防由TRPV3調節的疾病、病症和/或障礙的方法。