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Polymeric proteins refer to polymerase chains, in which the polymerase chain can bind several antigens selected from the following groups: NGF and PGE2; NGF and TNF-alpha; NGF and IL-1beta, NGF and IL-6R; and the polymerized proteins composed of the above proteins and INM molecules. UNO membership, imaging agents, therapeutic agents and cytotoxicants; vectors and host cells; drug components including the above-mentioned proteins.
专利权人:
ABBOTT LABORATORIES
发明人:
GHAYUR, TARIQ,KAMATH, RAJESH V.,HONORE, MARIE P.
申请号:
CL2012000957
公开号:
CL2012000957A1
申请日:
2012.04.13
申请国别(地区):
CL
年份:
2013
代理人:
摘要:
The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.Proteína de unión que comprende cadena polipeptidica donde dicha cadena puede unir un par de antígenos seleccionados del grupo formado por NGF y PGE2; NGF y TNF-alfa; NGF y IL-1beta y NGF y il-6R; conjugado de proteína de unión que comprende la proteína antes mencionada y una molécula de inmunoadhesión, un agente para obtener imágenes, un agente terapéutico y un agente citotoxico; vector y célula huésped; composición farmacéutica que comprende la proteína antes dicha.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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