EXPRESSION DE NA+/K+-ATPASE DANS UNE DYSPLASIE DU COL DE L'UTERUS ET UN CANCER DU COL DE L'UTERUS

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专利权人:

VENTANA MEDICAL SYSTEMS; INC.

发明人:

NITTA, HIROAKI,GROGAN, THOMAS M.,MILLER, PHILLIP

申请号：

CA2634896

公开号：

CA2634896C

申请日:

2006.12.27

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present disclosure provides methods ofdiagnosing cervical dysplasia and cervical cancer by detect-ingNa+, K+-ATPase expression. For example, it is demon-stratedherein that expression of the Na+, K+-ATPase .beta.1-sub-unitincreases in cervical dysplasia and cervical cancer, rel-ativeto normal cervical tissue. Also provided are methodsof treating cervical dysplasia and cervical cancer by decreas-ingthe biological activity of the Na+, K+- ATPase. For ex-ample,therapeutically effective amounts of one or more Na+,K+-ATPase inhibitors can be applied to the cervix to treatcer-vical dysplasia and cervical cancer.

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中国工程科技知识中心

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http://www.ckcest.cn/home/