Ertl, Peter Franz,Tite, John Philip,Van Wely, Catherine Ann
申请号：
AU2012201827
公开号：
AU2012201827A1
申请日:
2012.03.28
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2012201827A120120419.pdf#####ABSTRACT The present invention relates to virus vectors comprising oligonucleotides encoding HIV polypeptides, more particularly wherein the virus vector is an adenovirus. In particular, such adenoviruses are non-human primate adenoviruses such as simian adenoviruses, more particularly chimpanzee adenoviruses. In particular the invention relates to adenovirus vectors which comprise HIV polynucleotide sequences which encode multiple different HIV antigens, for example two or three or more HIV antigens. The invention further relates to methods of preparing the virus vectors, to the virus vectors produced by the methods and to the use of the vectors in medicine especially prophylactic or therapeutic vaccination.
