The syringe 1 with a needle includes a needle tube 3 having a needle tip 3 a that can puncture a living body, and a syringe 2. The syringe 2 includes a main body 6 filled with a medicine, a fixing portion 7 that fixes the needle tube 3 in a state where the needle tip 3a of the needle tube 3 is protruded, and a connection portion 12 that connects the fixing portion 7 and the main body 6. . The connection portion 12 is provided with a holding hole 13 into which the proximal end portion 3b of the needle tube 3 is inserted. After the proximal end portion 3 b of the needle tube 3 is inserted into the holding hole 13, at least a part of the fixing portion 7 is formed of the resin 15 made of substantially the same material as the syringe 2, so that the needle tube 3 is attached to the fixing portion 7. Fixed.針付きシリンジ1は、生体に穿刺可能な針先3aを有する針管3と、シリンジ2と、を備えている。シリンジ2は、薬剤が充填される本体6と、針管3の針先3aを突出させた状態で針管3を固定する固定部7と、固定部7と本体6が接続する接続部12とを有する。接続部12には、針管3の基端部3bが挿入される保持孔13が設けられている。針管3の基端部3bを保持孔13に挿入した後に、シリンジ2と実質的に同一の材料からなる樹脂15で固定部7の少なくとも一部を形成することで、針管3が固定部7に固定される。