MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG
发明人:
FIEBIG, HELMUT,NANDY, ANDREAS,CROMWELL, OLIVER
申请号：
CA2549573
公开号：
CA2549573C
申请日:
2004.12.01
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to a a cytochrome c-reporter fusion proteinconstructcomprising a modified cytochrome c protein which targets the mitochondria andhas areduced ability to induce apoptosis in a living cell. The invention alsorelates to nucleicacid constructs encoding such protein fusions and cells stably transfectedwith suchconstructs. The stably transfected cells of the invention can be used inassays to detectapoptosis.
