STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN;UNIVERSITEIT UTRECHT
发明人:
ROTTIER, PETRUS JOSEPHUS MARIE,DE HANN, CORNELIS ALEXANDER MARIA,HAIJEMA, BERT JAN,BOSCH, BEREND JAN
申请号：
HU0400042
公开号：
HU228121B1
申请日:
2002.05.17
申请国别(地区):
HU
年份:
2012
代理人:
摘要：
The invention relates to the field of coronaviruses and diagnosis, therapeutics, and vaccines derived thereof. Methods are shown for at least in part inhibiting anti-parallel coiled coil formation of a coronavirus spike protein wherein the methods include decreasing the contact between heptad repeat regions of the protein. The invention provides a peptide including a heptad repeat region of a corona viral spike protein and/or a functional fragment and/or an equivalent thereof. The invention also provides antibodies and inhibiting compounds.
