The present disclosure provides articles having a polymeric substrate with a plurality of solid and/or hollow microneedles extending therefrom. Each solid microneedle is formed by a molding process and the microneedle has body with first and second cavities extending therein. The hollow microneedles are formed by removing a portion of the polymeric material disposed between the first cavity and the second cavity. A method for determining the location of a microneedle in an article comprising solid microneedles is also provided. The method comprises directing electromagnetic radiation toward an article comprising a plurality of microneedles and imaging the article.本發明提供具有一聚合基板之物品,該聚合基板具有自其延伸之複數個實心及/或中空微針。每一實心微針係由一模製製程而形成且微針具有本體,第一及第二空腔在該本體中延伸。該等中空微針係藉由移除安置於該第一空腔與該第二空腔之間的聚合材料之一部分而形成。亦提供一用於判定一包含實心微針之物品中的微針之位置的方法。該方法包含將電磁輻射導向一包含複數個微針之物品及對該物品成像。10‧‧‧物品12‧‧‧基板14‧‧‧第一側面16‧‧‧第二側面20‧‧‧微針22‧‧‧本體24‧‧‧微針基底26‧‧‧尖端30‧‧‧第一空腔32‧‧‧第一開口34‧‧‧側壁36‧‧‧第一末端39‧‧‧第一空腔之第一點40‧‧‧第二空腔42‧‧‧第二開口44‧‧‧側壁46‧‧‧第二末端48‧‧‧倒角49‧‧‧第二空腔之第二點50‧‧‧變薄區域h‧‧‧高度x‧‧‧中心軸w‧‧‧寬度
