ATP SYNTHASE INHIBITORS AND STEROID ALKALOIDS AND USES THEREOF AS ANTIMICROBIAL AGENTS AND AS POTENTIATORS FOR AMINOGLYCOSIDES AGAINST PATHOGENIC BACTERIA
MARSAULT, ERIC,MALOUIN, FRANCOIS,CHAGNON, FELIX,GUAY, ISABELLE,BOULANGER, SIMON
申请号:
CA2970997
公开号:
CA2970997A1
申请日:
2014.12.23
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention provides bacterial ATP synthase inhibitors such as a compound of formula (I): (Formula (I)) (A) in combination with an aminoglycoside antibiotic for preventing or treating a bacterial infection in a subject or (B) (a) for preventing or treating an infection caused by an electron transport-deficient bacteria in a subject or (b) for the disinfection, sterilization and/or antisepsis of an object contaminated with an electron transport-deficient bacteria. There are provided compositions and kits using such compounds and inhibitors.