DONGGUK UNIVERSITY GYEONGJU CAMPUS INDUSTRY-ACADEMY COOPERATION FOUNDATION
发明人:
CHO, CHEONG WEON,조정원,KIM, YOUNG HO,김영호,KANG, JONG SEONG,강종성,PARK, YONG KI,박용기
申请号：
KR1020120013066
公开号：
KR1020130091826A
申请日:
2012.02.09
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A pharmaceutical composition is provided to enhance the interaction of drugs using a medicinal herb extract and pseudoephedrine, thereby increasing an effect of treating allergic rhinitis and to reduce side effects of the drugs and the frequency of administration.CONSTITUTION: A sustained release pharmaceutical composition for preventing or treating allergic rhinitis contains pseudoephedrine a medicinal herb extract including Atractylodis rhizoma alba, Angelicae koreanae Radix, Ledebouriellae radix, Scutellariae Radix, and Atractylodes macrocephala Koidzumi hydroxypropyl methyl cellulose as a release controller and micro crystalline cellulose, soft silicic acid anhydride, and magnesium stearate as pharmaceutical excipients. A pharmaceutical formulation for preventing or treating allergic rhinitis contains the pharmaceutical composition. The pharmaceutical formulation is manufactured in the form selected among a tablet, a pill, a granule, and a capsule.COPYRIGHT KIPO 2013[Reference numerals] (AA) Elution rate(%) of pseudoephedrine (BB) Example 1-1 (CC) Comparative example 1-6 (DD) Formulation on sale본 발명에 따른 약학 조성물은 한방 생약 추출물 및 슈도에페드린의 복합제제를 이용하여 약물 상호간의 작용을 증대시킴으로써, 알러지성 비염의 치료효과를 증가시키되, 약물의 부작용을 최소화할 수 있으며, 약물의 서방형 방출을 가능하게 하여 최대 12시간까지 약효가 지속됨으로써 약물의 1일 복용 투여 횟수를 줄이는 효과가 있다.
