Ranjani V. Parthasarathy;Katie F. Wlaschin;Alan R. Dombrowski;Matthew T. Scholz
发明人:
Katie F. Wlaschin,Alan R. Dombrowski,Matthew T. Scholz,Ranjani V. Parthasarathy
申请号：
US12775197
公开号：
US08460689B2
申请日:
2010.05.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A method of moisturizing while decolonizing mammalian tissue, the method comprising applying a multi-valent cationic antiseptic composition to the tissue, and applying a moisturizer composition to at least a portion of the same tissue； wherein the mammalian tissue is oral tissue of a subject； wherein the multi-valent cationic antiseptic is other than a metal ion； and wherein the applied compositions essentially exclude any component which causes a precipitate when combined with a multi-valent cationic antiseptic contained in the multi-valent cationic antiseptic composition when tested according to Test Method F, and/or wherein the moisturizer composition is such that a log reduction in the number of viable bacterial cells of at least 2 is provided when 106 cfu of Pseudomonas aeruginosa are combined with a mixture 1.1 g of the moisturizer composition and 1.5 g of the multi-valent cationic antiseptic composition containing 0.12 weight percent of the multi-valent cationic antiseptic according to Test Method B； an oral care kit comprising a composition comprising the multi-valent cationic antiseptic and the moisturizer composition； and a method of moisturizing oral tissue of a patient requiring intubation using the moisturizer composition and an endotracheal tube coated or impregnated with a cationic antiseptic are provided.
