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軟骨障害治療用化合物
专利权人:
小野薬品工業株式会社
发明人:
小櫃 徹夫,谷 耕輔,杉原 光,西浦 昭雄,藤村 心成
申请号:
JP2013528003
公开号:
JP5962657B2
申请日:
2012.08.03
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
The present invention provides a compound of which active form is represented by a formula (A). and which can be injected into a joint cavity which is an affected part of disorders and can be accumulated in the joint cavity to exert the pharmacological effect thereof in a sustained manner, for the purpose of ameliorating cartilage disorders without developing any side effect. A compound according to the present invention, which is represented by a formula (I): (wherein all of symbols are as defined in the description), is a compound that can achieve the above-mentioned purpose. This compound does not exhibit any side effect on the cardiovascular system even when the compound is administered in an effective amount for exhibiting a cartilage regeneration activity, and is therefore extremely useful as a safe and effective preventive and/or therapeutic agent for cartilage disorders. Since a suspension produced using this compound can be injected without requiring the incision of the affected part, it can reduce the burden on patients, and is extremely useful as a medicinal agent.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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