COLIN HISLOP,JOAQUIM TRIAS,DEBRA ODINK,BERNADINE FRASER,SCOTT CHADWICK
申请号：
BRPI1007032
公开号：
BRPI1007032A2
申请日:
2010.01.08
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
Niacin drugs are frequently utilized as a therapeutic to treat CVD, increase HDL levels, and/or decrease TG levels. As disclosed herein, it has been found that administration of one or more sPLA2 inhibitors in combination with one or more niacin drugs unexpectedly results in a synergistic increase in HDL levels and a synergistic decrease in TG levels. Therefore, compositions, methods, and kits are provided for treating CVD, increasing HDL levels, decreasing TG levels, and improving HDL/LDL ratios.
