REED, ROBERT A.,理德 罗伯,理德 羅伯,SU, DAISHUI,苏大水,蘇大水,理德 罗伯,理德 羅伯
申请号：
TW107119887
公开号：
TW201841622A
申请日:
2013.02.18
申请国别(地区):
TW
年份:
2018
代理人:
摘要：
The present invention relates to a formulation of thermosensitive liposomes, and more specifically to a formulation of liposomes comprising phospholipids and a surface active agent, wherein the liposomes support long term storage at temperatures less than or equal to about 8 ℃, control degradate formation to maximize product potency and release their contents at mild hyperthermic temperatures. Methods of making formulations are also described.本發明係關於熱敏性脂質體之調和物，更具體地說係關於包含磷脂及表面活性劑之脂質體的調和物，其中該等脂質體協助在低於或等於約8℃之溫度下的長期貯存、控制降解物(degradate)形成以最大化產物效力，及在溫和體溫過高的溫度(hyperthermic temperature)下釋放其包含物。本發明亦描述製造調和物之方法。
