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Substituted spirocyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists
专利权人:
Heptares Therapeutics Limited
发明人:
Giles Albert Brown,Miles Stuart Congreve,Mark Pickworth,Benjamin Gerald Tehan
申请号:
US16295364
公开号:
US10759751B2
申请日:
2019.03.07
申请国别(地区):
US
年份:
2020
代理人:
摘要:
This invention relates to compounds that are agonists of the muscarinic M1 receptor or M1 and M4 receptors and which are useful in the treatment of muscarinic M1 or M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formulawherein Q4, Q5, R5, p, V, Q1, Q2, X1, X2 and W are defined herein.
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http://www.ckcest.cn/home/
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