Disclosed are methods of reducing the incidence of oxidative stress in infants, toddlers, and children using nutritional compositions including human milk oligosaccharides. The nutritional compositions including the human milk oligosaccharides are effective at reducing inflammation and the incidence of inflammatory diseases.本發明揭示使用包括人乳寡醣之營養組合物減少嬰兒、幼兒及孩重之氧化壓力影響的方法。包括該等人乳寡醣之該等營養組合物有效地減少發炎及發炎疾病之發生率。