An airflow system with temperature and humidity control is provided, comprising a cyclic regeneration unit, at least one air supply unit and at least one air return unit. The humidity and temperature of the air circulating inside the system is adjusted via the cyclic regeneration unit. By designing angles of the air output from the air supply unit, it forms turbulence. And, the air returns back to the cyclic regeneration unit via the air return unit. In order to form the turbulent flow efficiently within an enclosed space, an air supply channel does not overlap with an air return channel orthographically, and pressure of the air exiting from the air supply channel is higher than that flowing into the air return channel such that pressure of the enclosed space is positive for preventing outside air flows into the enclosed system and affecting the humidity and temperature of the system.
