GAO, Min,GARDINER, David F.,LEMM, Julie A.,MCPHEE, Fiona,VOSS, Stacey A.
申请号:
USUS2011/046285
公开号:
WO2012/018829A1
申请日:
2011.08.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit Hepatitis C virus (HCV), compositions comprising such compounds, and methods for treating hepatitis C using such combinations. To achieve maximal efficacy and to potentially eradicate the virus, it will be critical to utilize combination therapies, especially those targeting distinct HCV viral targets. In vitro replicon-based combination studies have shown that additive to synergistic effects can be achieved with various combinations of HCV inhibitors.La présente invention concerne de manière générale des composés antiviraux, et concerne plus spécifiquement des combinaisons de composés capables d'inhiber le virus de l'hépatite C (VHC), des compositions contenant ces composés et des procédés de traitement de l'hépatite C au moyen de ces combinaisons.